Ovarian hydatid cyst - systematic review of clinicopathological and immunohistochemical characteristics of an unusual entity Ludmila Lozneanu, Raluca Anca Balan, Simona Eliza Giusca, Irina-Draga Caruntu, Cornelia Amalinei, Adriana Benign cancer liver Primary ovarian hydatid disease HD is a rare entity, produced by the larval stage of Echinococcus granulosus.
HD commonly involves liver, lung, abdomen cavity, spleen and is unusually identified in pelvic organs. Based on our knowledge, the paper reviews 27 literature reports of ovarian Benign cancer liver, diagnosed during the last 20 years, providing a valuable database.
Patients ages ranged between years, the gross appearance was that of mm diameter hydatid cysts HCs According to these reports, ovarian HD has non-specific clinical manifestations, such as abdominal or pelvic pain, nausea, dysmenorrhea or amenorrhea. Ovarian HC microscopic pattern is characterized by three layers: pericyst or adventitia host origingerminal layer endocystand laminated membrane ectocyst.
The immunoreaction triggered by parasites is initially rich in macrophages and neutrophils, followed by eosinophils and lymphocytes, with numerous cluster of differentiation 8 CD8 -positive T-cells in active lesions and progressive forms.
In conclusion, the ovarian location of HD should be considered in any differential diagnosis of a cystic lesion, while it does not exclude synchronous ovarian tumors. These cases reinforce the necessity of better measures of prophylaxis and screening of HD in endemic areas.
The most common entities are gliomas, craniopharyngiomas and embryonal tumors, including primitive neuroectodermal tumors of the CNS, such as medulloblastoma. Proper management of malignancies requires a histological diagnosis, especially in childhood, since diagnostic errors have a significant negative influence on the treatment and subsequently on the patient s care.
Experimental research conducted in the last years regarding the genomic and epigenetic landscape of pediatric brain tumors has provided considerable help in understanding their pathogenesis. New mutations and new signaling pathways have been associated with pediatric neoplasia, according to recent studies. Current therapeutic protocols recommend triple therapy, consisting in the surgical resection of the tumor, radiotherapy and chemotherapy.
Although immunotherapy and gene therapy continue to be a challenge, benign cancer liver studies are needed in order to confirm their promising role in the management of pediatric brain tumors. If incidence trends continue, the annual number of HPV-positive benign cancer liver cancers is expected to overcome the annual number of cervical cancers by the yearin the Benign cancer liver.
Aim: The aim of this paper is to review the recent data about several topics including risk factors of HPV-positive OPSCCs, guidelines in diagnostic evaluation, treatment, prognosis and prevention strategies, through prophylactic HPV vaccine on both sexes. Nowadays, HPV detection is a clinical standard of care for oropharyngeal malignancy by reporting tumors as HPV positive or p16 positive.
- Liver hemangioma, or hepatic hemangioma, is a benign tumour in the liver.
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The extremely rare concha of Zuckerkandl reviewed and reported Mugurel Constantin Rusu, Mihai Sandulescu, Carmen Aurelia Mogoanta, Adelina Maria Jianu Background: Usual descriptions indicate three or maximum four nasal turbinates conchae attached to the lateral nasal wall.
The middle, superior and, occasionally, supreme ones belong to the ethmoid bone. Few authors include in descriptions the concha that Zuckerkandl described as the fourth or supreme ethmoidal turbinate.
Translation of "adenoma" in Romanian
Despite some inconsistencies in Zuckerkandl s description, the concha bearing his name lies above Santorini s supreme concha, which, in turn, is above Morgagni s superior concha. Few other authors preferred to name Santorini s concha as the first supreme one and Zuckerkandl s concha as the second supreme one. Methods: We retrospectively documented, with various purposes, the archived cone-beam computed tomography files of patients.
Results: We found in just one case a unilateral sequence of five nasal turbinates. On the opposite side, only four turbinates were detected. Three-dimensional renderizations confirmed benign cancer liver when two supreme turbinates are found, they are joined in a common posterior tail, which, in turn, joins the tail of the superior turbinate. Conclusions: Co-existence of two supreme conchae could either indicate their origin from different ethmoturbinals, or from the split of a commonly unique supreme one.
Hemangiom hepatic – cauze, simptome, tratament
Zuckerkandl hpv cream side effects concha deserves therefore to be considered when anatomical descriptions, or studies, are delivered. Systemic lupus erythematosus SLE is the prototype of connective tissue diseases that can present the complete spectrum of neurological and psychiatric dysfunctions.
The precise etiological diagnosis of neuropsychiatric systemic lupus erythematosus NPSLE is rather difficult to be established and it is still controversial the exact timing of neuropsychiatric NPS events: either central nervous system CNS is the initial target of autoimmune abnormalities, either NPS symptoms are a part of multisystem involvement.
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Neuroinflammation, consequent to blood-brain barrier BBB damage, local and systemic production of autoantibodies, determine neuronal injury and apoptosis, further responsible for diffuse cerebral events, mostly cognitive dysfunction and psychotic disorder. Moreover, SLE complications or therapy complications can interfere and contribute to complex clinical manifestations that can be present in SLE patients.
Understanding the role of each pathogenic way can provide not only an early diagnosis, but a more accurate therapeutic approach of these patients. Toxicity and health impact of nanoparticles. In search of new therapeutic strategies for the ischemic brain, cell-based therapies offered new hope, which has been, in the meanwhile, converted into a more realistic approach recognizing difficulties related to unfavorable environments causing low survival rates of transplanted neuronal precursors.
Stem cell therapies benign cancer liver based on the transplantation of neuronal precursor cells NPCsadult stem cells propagated in cell culture or inducible pluripotent cells iPSCs obtained from patients and trans-differentiated into neural benign cancer liver.
Of these, autologous iPSCs have the advantage to be used in stroke patients because they do not raise ethical concerns and the risk of graft rejection is low. However, the use of stem cells for stroke benign cancer liver in humans has to take into account many factors including, dosage, route of administration, benign cancer liver and side effects. For example, nanoparticles NPs may increase the efficacy of drugs and therapeutic cells delivery benign cancer liver the diseased brain. Medication dosages are generally determined by clinical trials done in relatively young, healthy people.
However, in vivo and clinical data evaluating the toxic effects of NPs on neural cells are still scarce especially in the aged brain, which has a decreased homeostatic capacity and a reduced ability to cope with internal benign cancer liver environmental stress, as compared to the young brain.
Previous studies in rodents indicate that aging along with neurodegenerative diseases may promote a proinflammatory state and leads to the development of gliosis in the aged brains. On the other hand, the nonspecific interaction between the shell of NPs and papilloma sulla lingua proteins leads to the adsorption of opsonins on their surface, forming the so-called corona, thereby becoming ideal candidates to attract phagocytic microglia resulting in NPs engulfment and thus exacerbating neuronal death.
Therefore, when designing NPs benign cancer liver clinical use, it should be considered that their systemic administration is associated with potential risks, especially in the aged subjects. Recently, NPs have been shown in recent years to play a crucial role in cell signaling processes involved in stroke recovery. Extracellular vesicles EVs are secreted by virtually all type of cells in the body and have been benign cancer liver to reflect the physiological and metabolic status of the host cells.
Zoltan Pavai - Referințe bibliografice Google Academic
Thus, understanding the disease-specific contents of EVs would enable the discovery of novel predictive biomarkers. Basic biology and clinical perspective PDF 7.
The complex biological mechanisms occurring in hypertrophic scarring are still barely understood. To date, there is no satisfactory description of hypertrophic fibroblasts. Therefore, in the present study we focused on the comparatively characterization of the fibroblasts residing in different regions of hypertrophic scars.
These cell populations were further were used for the evaluation of proliferation and migration capacity, for the gene and protein expression of extracellular matrix protein type I collagen and fibronectin and for the presence of myofibroblasts. Our results demonstrated that perilesional and intralesional fibroblasts isolated from hypertrophic scars could be considered as distinct populations, having different properties.
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Thus, the intralesional fibroblasts had an increased proliferation capacity and increased gene and protein expression of collagen I and fibronectin. However, the perilesional fibroblasts had augmented mobility as revealed by in vitro scratch test and contained a higher percentage of myofibroblasts [alpha-smooth muscle actin alpha-SMA high cells], in comparison to the intralesional population.
In conclusion, our data could provide an explanation regarding the inconsistent benign cancer liver of topic therapies benign cancer liver hypertrophic scars.
Among classical pancreatic markers that ascertain the histopathology, new emerging targets have been proposed for both diagnostic and prognostic purposes.